Bongkrekic acid-13c28
WebDec 18, 2024 · Poisoning incidents caused by bongkrekic acid (BA), one of the metabolites of Burkholderia gladioli pathovar cocovenenans ( B. cocovenenans ), have been reported in Indonesia, Mozambique, and China. The reported case fatality rates averaged 60%, 32%, and 26.5%, respectively. WebMolecular Weight: 486.61 (free acid) Molecular Formula: C 28 H 38 O 7 Solubility: Miscible with DMSO. Physical Properties: Solution at 1 mg/mL (2 mM) in 0.01M Tris buffer pH 7.5 (contains 1 mg net bongkrekic acid per mL) Purity: 97% by HPLC NMR (Conforms) Storage Temperature: -20° Stability: Stable for 1 year from date of purchase as supplied.
Bongkrekic acid-13c28
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WebOct 1, 1982 · INTRODUCTION Bongkrek acid and toxoflavin are toxins which became well-known in connection with cases of food poisoning by the consumption of tempe bongkrek, one of the many fermented foods in Indonesia. It is made by fermentation of partially defatted coconut with Rhizopus oligosporus. WebFor example, bongkrekic acid, or exposure to uncouplers such as p -trifluoromethoxy carbonyl cyanide phenyl hydrazone (FCCP) to moderate Ca 2+ uptake during excitotoxicity, correspondingly moderate mitochondrial dysfunction and cell death in the short term. 105,106 However, by preventing mitochondrial adenylate exchange, and by uncoupling …
WebC 28 H 38 O 7. CAS number: 11076-19-0. EU number: Not assigned. Fermentek product code: BON. Source: Pseudomonas gladioli. WebBongkrekic acid is a little-known toxin and source of food poisoning that is produced by the bacterium Burkholderia gladioli. These bacteria flourish …
WebJul 9, 2015 · Bongkrekic Acid In humans though, toxicity manifests within a few hours of ingestion and presents with abdominal pain, general discomfort, sweating, fatigue, and eventual coma. Death can occur within 24 hours. WebMar 2, 2024 · Bongkrekic acid is a heat-stable, highly unsaturated tricarboxylic fatty acid with a molecular weight of 486 kDa. Outbreaks …
WebSep 20, 2024 · Bongkrekic acid is produced by the bacterium, Burkholderia cocovenenans, which is ubiquitous in the soil and plants. It grows best at 37°C and can optimally produce bongkrekic acid at about 26°C. Bongkrekic acid is heat-stable and cannot be removed by washing. Patients suffering from bongkrekic acid poisoning may show symptoms … ge microwave model pvm9215skss manualWebNov 22, 2004 · Bongkrekic acid (1) 1 is a natural toxic antibiotic produced by the microorganism Pseudomonas cocovenenans.The high toxicity of 1 has been attributed to its affinity for the ATP/ADP translocator protein residing in the mitochondrial inner membrane, which prevents oxidative phosphorylation (IC 50 = 2 × 10 −8 M). 2 Furthermore, by … dd services in oregonWebBongkrekic acid (BA) is a sort of fatty acid produced by the bacterium Burkholderia gladioli pv. Cocovenenans, which survives in corn flour and coconut products (Travis M Falconer et al., 2016). First documented food poisoning case due to BA happened in Indonesia in 1895. ge microwave model pem31sm3ssWebDec 21, 2024 · Bongkrekic acid (11076-19-0) is a p potent inhibitory ligand of the mitochondrial adenine nucleotide translocase (ANT).1?Inhibits mitochondrial permeability transition pore opening.2,3?Delivery of bongkrekic acid to the mitochondria prevents apoptosis in HeLa cells.4 Uses ge microwave model wes1450dmbbWebBongkrekic acid is a mitochondrial ANT toxin and is reported primarily in outbreaks of food-borne poisoning involving coconut and corn. It should be considered in outbreaks of food … ge microwave model pvm9179srssWebThe inhibitors atractyloside and bongkrekic acid trap the AACs in two different conformations known as the c- and m-state where the carrier is open to the cytoplasmic … ge microwave model sca1001hss 01WebDec 1, 2024 · Bongkrekic acid (BKA) inhibits adenine nucleotide translocator (ANT) and suppresses ADP/ATP exchange in the mitochondrial inner membrane. Previously, we … dds family investment co