WebThe Emory Down Syndrome Project and the Study of Down Syndrome and Congenital … WebJan 30, 2024 · The multidomain CCCTC-binding factor (CTCF), containing a tandem array of 11 zinc fingers (ZFs), modulates the three-dimensional organization of chromatin. We crystallized the human CTCF DNA-binding domain in …
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WebMar 22, 2024 · CTCF is a zinc-finger protein that was initially described as a transcriptional repressor of the Myc gene ( Klenova et al., 1993; Lobanenkov et al., 1990 ). It is conserved among bilaterians, and phylogenetic analyses suggest an early origin in the evolution of Metazoa ( Heger et al., 2012 ). WebSearch Results for all work with filters: Genome Research; Biology sievers sports medicine
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WebMar 9, 2024 · 1 Department of Biology, Emory University, 1510 Clifton Road NE, Atlanta, GA 30322, USA. ... (CTCF)/cohesin binding sites in pluripotent cells. Elimination of hemimethylation causes reduced frequency of chromatin interactions emanating from these sites, suggesting a role for hemimethylation as a stable epigenetic mark regulating CTCF … WebSep 29, 2024 · Transgenerational transmission of epiphenotypes is poorly understood. Here we show that exposure of pregnant mouse F0 females to BPA results in obesity in the F2 progeny due to increased food intake and leptin resistance. This epiphenotype can be transmitted up to the F6 generation and disappears in F7. Analyses of chromatin … WebAccessing eBranch. First-time users can access eBranch using their current ART … the power of the now pdf