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Fsip1 regulates autophagy in breast cancer

WebFeb 27, 2024 · Therefore, we sought to establish a correlation between the clinico … WebFSIP1 regulates autophagy in breast cancer Caigang Liua,1, Lisha Sun a, Jie Yang , …

Over-expression of FSIP1 promotes breast cancer progression

WebFibrous sheath interacting protein 1 (FSIP1) is a cancer antigen expressed in the majority of breast cancer tissues and is associated with poor prognosis. However, the role of FSIP1 in the progression and drug sensitivity of triple-negative breast cancer (TNBC) has not been explored. Here, we show that FSIP1 deficiency by shRNA-mediated knockdown or … WebJan 11, 2024 · Additionally, autophagy seems to exert a dual role in luminal breast cancer, and also triple-negative BC . Takabe et al. demonstrated that high NRF2 tumors were associated with high infiltration of DCs by conducting in silico analyses in 5,443 breast cancer patients from several large patient cohorts . Besides, it is likely that different ... follow up proposal letter sample https://bowden-hill.com

FSIP1 regulates autophagy in breast cancer PNAS

WebFibrous sheath interacting protein 1 (FSIP1) has been identified as a poor prognostic indicator of breast cancer. Here, we report that FSIP1 positively regulates the proliferation and invasion of triple-negative breast cancer … WebFibrous sheath interacting protein 1 (FSIP1) is frequently activated in a variety of tumors including breast cancer. However, the clinical significance of FSIP1 in hormone receptor (HR)-positive breast cancer is unclear. We analyzed the expression and clinical significance of FSIP1 in human breast c … WebMar 2, 2024 · Macroautophagy (herein referred to as autophagy) is a key homeostatic pathway that facilitates the degradation and recycling of cellular material 1. The benefits of stimulating autophagy in ... follow up question def

FSIP1 regulates autophagy in breast cancer - PubMed

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Fsip1 regulates autophagy in breast cancer

FSIP1 regulates autophagy in breast cancer

WebDec 3, 2024 · Fibrous sheath interacting protein 1 (FSIP1) has been identified as a poor … WebNov 1, 2024 · Autophagy plays multiple and often disparate roles during different stages …

Fsip1 regulates autophagy in breast cancer

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WebFeb 27, 2024 · FSIP1 is over-expressed in breast cancer cell lines and tumor tissues. FSIP1 protein expression markedly increased in every breast cancer cell line when contrasted to the HMECs (Fig. 1a ... WebFeb 27, 2024 · Recent experiments from our group found that FSIP1 could bind with Her2 and regulate breast cancer growth and invasiveness 6. Other studies have reported that FSIP1 associates with PKA 7 and SRC-3 8, ... FSIP1 regulates autophagy in breast cancer. Liu C, Sun L, Yang J ...

WebAlthough the mechanisms of autophagy have not yet been fully elucidated, emerging evidence suggests that it plays a dual role in breast cancer and in maintaining the activity of breast cancer stem cells (CSCs). However, it may play a complex role in breast CSC therapy. Breast CSCs, a population of cells with the ability to self-renew ... WebAug 2, 2013 · Aim: The study aimed to identify and characterize highly specific breast tumor biomarkers. Methods: A microarray data set comprised of 513 diverse normal and tumor mRNA samples was analyzed to identify breast tumor biomarkers with minimal expression in normal tissues. Results:FSIP1 was identified as a breast tumor biomarker with …

WebApr 1, 2015 · Results. Expression of FSIP1 protein was significantly higher in breast cancer tissues compared to tumor-adjacent tissues (p = 0.001).Strong correlation was observed between FSIP1 expression and human epidermal growth factor receptor 2 (Her-2) or Ki67 expression in breast cancer (p = 0.027 and 0.002, respectively).Similarly, serum level of … WebAug 5, 2024 · High FSIP1 expression is associated with drug resistance in triple-negative …

WebFSIP1 deficiency promoted autophagy, enhanced AMP-activated protein kinase …

WebFibrous sheath interacting protein 1 (FSIP1) is a cancer antigen expressed in the majority … eightchan siteWebFeb 25, 2024 · 2.1. MA Inhibits Breast Cancer Cell Proliferation. To explore the effects of MA (Figure 1 a) on breast cancer cell proliferation, we performed the MTT assay on MCF-10A, MDA-MB-231, and MCF-7 cells at concentrations of 0, 0.5, 1, 2, 4, and 8 μM for 24 h.The results displayed that MA had cytotoxic effects on MDA-MB-231 and MCF-7 cells … follow up psychiatric visit templateWebMar 25, 2024 · Autophagy types and process, and functional roles of autophagy in breast cancer. The main objective of autophagy or “self-eating” (Greek meaning) is to break down cytoplasmic components like macromolecules and organelles, in order to sustain cellular metabolism and to ensure cellular homeostasis [16, 38, 39].Some people described … follow up question 意味WebNov 30, 2016 · Furthermore, B7-H3 regulates glucose metabolism in breast cancer cells , suggesting that the B7-H superfamily, to which PD-L1 and B7-H3 belong or the immunoglobulin superfamily to which these and PD-1 all belong , could have important tumor metabolic effects, which is an area meriting additional investigations. Our RNA-seq … follow up question for interviewWebNov 1, 2024 · There is ample evidence that the majority of conventional therapies used to combat breast cancer induce autophagy (Table 1).Although autophagy is most often considered to be a protective mechanism that allows cells to evade apoptosis, it is clear that the nature of autophagy in response to anti-cancer modalities is a complex subject (Fig. … follow up questions definitionWebFSIP1 regulates autophagy in breast cancer Caigang Liua,1, Lisha Sun a, Jie Yang , … follow up questions 中文WebFSIP1 regulates autophagy in breast cancer Caigang Liu, Lisha Sun, Jie Yang, Tong … follow up questions to ask