Nphs2 cre

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August undefined, 2024

WebPodocin-Cre mice (designated Nphs2Cre) were obtained from Jackson (008205, B6. Cg-Tg (NPHS2-cre) 295Lbh/J). The Lonp1floxed mice (designated Lonp1fl/fl) were generous … Web008205 B6.Cg-Tg(NPHS2-cre)295Lbh/J These transgenic mice (commonly referred to as podocin-Cre mice) have expression of Cre recombinase directed to podocytes within …

008205 - 2.5P-Cre Strain Details - The Jackson Laboratory

Web10 jan. 2024 · scRNA-seq of BTBR ob/ob mouse kidneys with early DN. We generated BTBR ob/ob podocyte-reporter mice (BTBR.Cg-Lep ob/ob WiscJ;Gt (ROSA)26Sor tm4(ACTB−tdTomato,−EGFP)Luo;Tg(NPHS2-cre) 295Lbh; hereafter referred to as BTBR ob/ob or DN mice) to investigate the cellular and molecular changes that occur in DN. By … Web28 okt. 2024 · The epidermal growth factor receptor (EGFR) is expressed in numerous cell types in the adult mammalian kidney and is activated by a family of EGF-like ligands. EGFR activation has been implicated in a variety of physiologic and pathophysiologic functions. There is increasing evidence that aberrant EGFR activation is a mediator of progressive … over the garden wall watch

Podocyte-specific expression of Cre recombinase in transgenic mice

WebNphs2 Also Known As Podocin Cre Mice, supplied by The Jackson Laboratory, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS … WebNPHS2 pathogenic variants are the most common podocyte gene defects. Yet, pathogenic variants are found only in a minority of SRNS patients. No homozygotes or compound heterozygotes were observed in 377 biopsy confirmed late-onset FSGS [52].In three large worldwide analyses, NPHS2 pathogenic variants were found in roughly 10% of the … Web1 mei 2024 · By conventional structural and functional measures (histology by periodic acid-Schiff staining, albuminuria, and plasma creatinine), we did not detect significant … rand estate

006889 - Lck-Cre (Tg540-I) Strain Details - The Jackson Laboratory

Nphs2 Podocin Cre Mice The Jackson Laboratory Bioz

Web7 jun. 2016 · Podocyte confetti reporter mice. To study the potential ability of podocytes to regenerate following the induction of experimental FSGS, adult (8–10 wk old) NPHS2 Cre /Confetti TG/WT (podocin-cre/confetti) reporter mice, generously provided by Dr. Katalin Susztak (University of Pennsylvania, Philadelphia, PA) and described by Tao et al. (), … Web1 mrt. 2024 · Of these significant, differentially regulated genes, 139 were up-regulated and 91 were down-regulated in glomeruli of NPHS2-Cre +/+ mice as compared with that … over the garden wall wirt and beatriceWebFull Sequences from Addgene (1) Based on next-generation sequencing (NGS) results where indicated (Addgene NGS Result), or assembled from reference sequences and/or … over the garden wall wart

"Web7 sep. 2024 · ARF6-flox mice with LoxP sites flanking exon 1 and 2 were crossed with Cre mice in which Cre recombinase was driven by the podocyte-specific podocin promoter … " - Nphs2 cre

Nphs2 cre

WebNPHS2-cre. 2024-11-19. B6.Cg-Tg(NPHS2-cre)295Lbh. 品系编号：GAP1021. 品系简称：NPHS2-cre. 品系特点：. NPHS2-Cre 小鼠可存活且可生育，Cre 重组酶的表达通过人 … Web10 okt. 2024 · Cyclization recombinase (Cre)는 타이로신 부위 특이적 재조합 효소 중 하나로, 두 DNA 인식 부위 사이의 부위 특이적 재조합을 촉매할 수 있다. Cre recombinase는 P1 …

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WebTg (NPHS2-cre/ERT2)#Mkas. Mutation details : A 2.5 kb human podocin (NPHS2) promoter (from BAC clone RP11-231PS) was used to drive expression of cre recombinase fused … Web11 feb. 2010 · Cre-mediated recombination. To determine the ability of Cre recombinase on tamoxifen-inducible selective recombination of loxP sites, we crossbred NPHS2–CreER …

WebPartial Sequences from Addgene (3) Addgene has sequenced portions of this plasmid for verification. The results are shown below. Leading primers are indicated on the first line … Web20 mrt. 2024 · NPHS2 Cre PAR-1 Active+/− mice were also in renal failure as evidenced by their significantly higher levels of serum creatinine and urea compared with littermate controls (Figure 4 c and d, respectively). Furthermore, NPHS2 Cre PAR-1 Active+/− mice died between the ages of 39 and 45 days (Figure 4 e).

Web19 mrt. 2024 · NPHS2-Cre +/-, Tsc2 wt/wt mice (Nphs2-Cre) and NPHS2-Cre-/-, Tsc2 flox/flox mice (Tsc2 flox/flox) were used as controls. F, flox; +, wt. ( B ) Primary cultured … Web15 aug. 2024 · Rosa26-CreERT2 小鼠种系能够通过体内他莫昔芬诱导对floxed基因表达进行时间控制。. 也就是在Rosa26位点插入了CreERT2基因使其能能够稳定表达，当进行他 …

WebIns2-cre: 胰脏β细胞: Lyz2-cre: 骨髓细胞系: Tagln-cre: 平滑肌细胞: AQP2-cre: 肾细胞和睾丸: Alb-cre: 肝: Lck-cre: 胸腺细胞: Fabp4-cre: 生殖腺和皮下脂肪组织: Myh6-cre（αMHC …

Web实验小鼠是目前应用最为广泛的一种实验动物，在探寻基因基础功能，疾病发病机制以及药物临床前筛选等方面有着十分重要的作用。其原因在于小鼠和人的基因具有极高的相似 … overthegardenwallwallpWebNphs2-CreERT2 品系全名 C57BL/6JSmoc- Nphs2tm1 (IRES-CreERT2)Smoc 目录号 NM-KI-00128 品系状态胚胎冻存加入购物车导出PDF 基因信息基因名 Nphs2 基因曾用名 … over the garden wall watch cartoon onlineWebCryo-Recovered Mouse Frozen Mouse Embryo #006889 Region Product Type Quantity Genotype Hemizygous or Non carrierfor Tg (Lck-cre)I540Jxm Price You Will Receive 2 carriers minimum Availability Mice Available In 12 Weeks. Contact Customer Service for more information. Order Now Details WHAT TO EXPECT A confirmation will be sent … over the garden wall yearWebindividual cell types. To further validate the clustering analysis results, we used Nphs2. Cre. mTmG, Scl. Cre. mTmG and Cdh16. Cre. mTmG mice as reporter lines to mark … over the gate forumWebThe NPHS2 gene provides instructions for making a protein called podocin. Podocin is primarily found in the kidneys, which are organs that filter waste products from the blood … r and e schoolWeb5 apr. 2014 · 肾小管组织特异性cre工具鼠目前已应用于肾小管基因敲除的cre工具鼠主要由以下启动子驱动，其中在近端小管中特异性较高的启动子为GGT，SGLT2，PEPCKKAP， … randers tegl proffWeb2 okt. 2024 · 4．前期基础： :NPHS2-Cre小鼠、足细胞β-catenin 基因敲除小鼠、mTOR 持续活化的 FKBP38 转基因小鼠及全身性PPARγ 基因敲除小鼠在内的多种肾小球损伤动物 … rande show