WebbIn this work, a liquid chromatography stability-indicating method was developed and applied to study the hydrolytic behavior of simvastatin in different pH values and … Webb1 apr. 2024 · dry mouth ear congestion fever flushed, dry skin frequent urge to urinate fruit-like breath odor headache increased hunger increased thirst increased urination joint pain loss of consciousness lower back or side pain muscle cramps, spasms, stiffness, pain, tenderness, wasting, or weakness nausea runny or stuffy nose sneezing sore throat …

Simvastatin (Simvastatin): Uses, Dosage, Side Effects ... - RxList

Webb10 mg. 20 mg. 40 mg. 80 mg. Dosage Considerations – Should be Given as Follows: Hypercholesterolemia (High Cholesterol) Usual dosage range: 5-40 mg orally once/day. Initial: 10-20 mg orally once/day in the evening. Patients at high CHD risk: Start 40 mg/day. Children under 10 years: Safety and efficacy not established. WebbSimvastatin, a prodrug, is converted to its active metabolite simvastatin acid (SVA), which is a substrate of the organic anion transporter protein OATP1B1. SLCO1B1 gene encodes OATP1B1 which mediates the hepatic uptake of statins and other exogenous and endogenous compounds (e.g. bilirubin and 17-β-glucuronosyl estradiol) for subsequent … porky baines

Simvastatin: Wirkung, Anwendung, Nebenwirkung

Webb13 nov. 2024 · Simvastatin belongs to a group of medicines known as statins (or HMG-CoA reductase inhibitors). It regulates the amount of cholesterol and other lipids made by your body. It does this by blocking the action of a certain enzyme (called HMG-CoA reductase) which your body needs to make the fats. This lowers your risk of heart and blood vessel … WebbSimvastatin is used to lower cholesterol if you’ve been diagnosed with high blood cholesterol.It’s also taken to prevent heart disease, including heart attacks and strokes.It belongs to a group of medicines called statins.. Your doctor may prescribe simvastatin if you have a family history of heart disease, or a long-term health condition such as … Webb4 apr. 2024 · Active Ingredient: simvastatin Company: Aurobindo Pharma - Milpharm Ltd. See contact details ATC code: C10AA01 About Medicine Prescription only medicine Healthcare Professionals (SmPC) Patient Leaflet (PIL) This information is for use by healthcare professionals Last updated on emc: 04 Feb 2024 Quick Links iris corsi