Tead4基因
WebNov 1, 2024 · Tead4是小鼠胚胎着床前发育过程中最早表达的转录因子之一,是滋养外胚层相关基因表达所必需的。 小鼠基因功能缺失研究显示通过位点特异性重组失活Tead4,导致胚胎发育受损和滋养外胚层特异性基因Cdx2和Gata3的表达下调;Cdx2和Gata3做为Tead4调控下游的平行通路 ... WebJun 14, 2024 · Tead4 is one of the earliest transcription factors expressed during mouse embryo preimplantation development and is required for the expression of TE-associated genes. Functional knock-out studies in mouse, inactivating Tead4 by site-specific recombination, have shown that Tead4-targeted embryos have compromised …
Tead4基因
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WebApr 8, 2024 · 点评 兰雨(暨南大学)、张维绮(中国科学院北京基因组研究所). 责编 兮. 造血干细胞(Hematopoietic stem cell,HSC)具有自我更新和分化为所有下游血细胞的能力,在整个生命周期中不断为机体提供新鲜血液【1】。在衰老过程中,HSC会发生髓系分化偏好、淋系分化减少、造血重建能力受损和克隆 ... Webtead2基因编码序列nm_001256658.2,tead2蛋白编码序列np_001243587.1,tead2基因又名etf; tead-2; tef-4; tef4,tead2基因,tead2蛋白,tead2抗体,tead2表达质粒,tead2基 …
WebJan 1, 2014 · 本课题拟在临床组织标本中,观察转录因子TEAD4表达与结直肠癌临床病理特征的关系;在细胞生物学实验中,研究基因干预TEAD4表达对结直肠癌细胞株生物学行 … WebNov 1, 2024 · Tead4是小鼠胚胎着床前发育过程中最早表达的转录因子之一,是滋养外胚层相关基因表达所必需的。 小鼠基因功能缺失研究显示通过位点特异性重组失活Tead4, …
Web与此一致,yap或taz 的激活或过表达增强tead依赖性基因 ... 此外,使用gal4报告系统和tead1,tead2,tead3和tead4的gal4融合,我们证明cpd3.1抑制yap诱导的所有四种tead … WebOncogene:研究阐明Hippo通路关键转录因子TEAD4特异性结合DNA机制 ... 的大沟与小沟;针对其中任一位点的突变会使得TEAD4在靶基因启动子上的占有率显着 ...
WebOct 6, 2024 · Abstract. TEA domain transcription factor 4 (TEAD4) is an important member of the TEAD family. As a downstream effector of the Hippo pathway, TEAD4 has essential roles in cell proliferation, cell survival, tissue regeneration, and stem cell maintenance. TEAD4 contains a TEA DNA binding domain that binds the promoters of target genes …
WebOct 6, 2024 · Abstract. TEA domain transcription factor 4 (TEAD4) is an important member of the TEAD family. As a downstream effector of the Hippo pathway, TEAD4 has … margin status for invasive carcinomaWebNov 25, 2008 · Function. Transcription factor which plays a key role in the Hippo signaling pathway, a pathway involved in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. The core of this pathway is composed of a kinase cascade wherein MST1/MST2, in complex with its regulatory protein SAV1, … margin standar proposalWeb我们已与文献出版商建立了直接购买合作。 你可以通过身份认证进行实名认证,认证成功后本次下载的费用将由您所在的图书 ... cup marche numero verde da cellularehttp://www.biofeng.com/gene/renyuan/TEAD4.html margin storeWeb基因别名: EFTR-2,MGC9014,RTEF1,TCF13L1,TEF-3,TEFR-1,hRTEF-1B 基因名: TEAD4 基因库序列号: BC015497 基因概览: This gene product is a member of the … margins melanoma in situWebNational Center for Biotechnology Information cup mantova ospedaleWebJul 28, 2024 · Both TEAD4 and its cofactor, yes-associated protein 1 (YAP1), are specifically expressed in cytotrophoblast (CTB) progenitors of a first-trimester human placenta. We also show that a subset of unexplained recurrent pregnancy losses (idiopathic RPLs) is associated with impaired TEAD4 expression in CTB progenitors. Furthermore, by … cup mantova prenotazione telefono